Estrogen production by fetal and infantile rat ovaries

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Estrogen production by fetal and infantile rat ovaries.

The de novo production of estrone and estradiol by the fetal and infantile rat ovary and its regulation by cAMP, LH and FSH were investigated. Basal estrogen secretion was not demonstrable before d 5 after birth. However, the fetal ovary was responsive to cAMP as early as 14 d old. Estrone was the main estrogen secreted. Steroid aromatase inhibitors inhibited cAMP-stimulated estrone secretion. ...

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ژورنال

عنوان ژورنال: Reproduction Nutrition Development

سال: 1993

ISSN: 0926-5287

DOI: 10.1051/rnd:19930205